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. 2016 Apr 26;6:25163. doi: 10.1038/srep25163

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Mouse abscess model with essB deletion mutant versus isogenic wild-type representative ST398 isolate. Number of mice used: n = 11/group. (A) Abscess areas on day 2 after infection. **p < 0.01 (unpaired t-test). (B) Representative abscesses on day 2 after infection. (C) H&E staining of abscess skin tissue harvested on day 4. (–), control without challenge. Note considerable infiltration of inflammatory cells and damage of the subcutaneous structure in the wild-type and essB mutant samples, noticeably stronger in the wild-type sample (arrows).