Table 2.
Demographic characteristics of participants in the CLIC pooled analyses of parental occupational paint exposure and the risk of leukemia in the offspring
| ALL (12 studies) | AML (10 studies) | |||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Case (n= 8835) | Control1 (n = 15486) | Case (n= 1357) | Control2 (n= 12443) | |||||
| n | %3 | n | %3 | n | %3 | n | %3 | |
|
| ||||||||
| Sex | ||||||||
| Boy | 4972 | 56.3 | 8634 | 55.8 | 713 | 52.5 | 6928 | 55.7 |
| Girl | 3863 | 43.7 | 6852 | 44.2 | 644 | 47.5 | 5515 | 44.3 |
| Age (years)4 | ||||||||
| 0–1 | 958 | 10.8 | 2272 | 14.7 | 376 | 27.7 | 2000 | 16.1 |
| 2–4 | 4109 | 46.5 | 6156 | 39.8 | 259 | 19.1 | 4610 | 37.0 |
| 5–9 | 2570 | 29.1 | 4507 | 29.1 | 313 | 23.1 | 3526 | 28.3 |
| 10–14 | 1198 | 13.6 | 2551 | 16.5 | 342 | 25.2 | 2231 | 17.9 |
| 15–17 | 0 | 0.0 | 0 | 0.0 | 67 | 4.9 | 76 | 0.6 |
| Year of birth | ||||||||
| 1970–1978 | 294 | 3.3 | 395 | 2.6 | 151 | 11.1 | 289 | 2.3 |
| 1979–1987 | 2555 | 28.9 | 4318 | 27.9 | 426 | 31.4 | 2943 | 23.7 |
| 1988–1996 | 3927 | 44.5 | 7226 | 46.7 | 578 | 42.6 | 6350 | 51.0 |
| 1997–2005 | 1936 | 21.9 | 3394 | 21.9 | 175 | 12.9 | 2710 | 21.8 |
| 2006–2011 | 123 | 1.4 | 153 | 1.0 | 27 | 2.0 | 151 | 1.2 |
| Child has Down Syndrome | ||||||||
| Yes | 103 | 1.2 | 6 | <0.1 | 89 | 6.6 | 4 | <0.1 |
| No | 8730 | 98.8 | 15479 | 100.0 | 1267 | 93.4 | 12438 | 100.0 |
| Missing | 2 | 0.0 | 1 | 0.0 | 1 | 0.1 | 1 | 0.0 |
| Maternal education | ||||||||
| Did not finish secondary education | 2327 | 26.3 | 3950 | 25.5 | 322 | 23.7 | 3479 | 28.0 |
| Completed secondary education | 3859 | 43.7 | 6619 | 42.7 | 664 | 48.9 | 5098 | 41.0 |
| Tertiary education | 2588 | 29.3 | 4756 | 30.7 | 358 | 26.4 | 3706 | 29.8 |
| Missing | 61 | 0.7 | 161 | 1.0 | 13 | 1.0 | 160 | 1.3 |
| Paternal education | ||||||||
| Did not finish secondary education | 2420 | 27.4 | 4266 | 27.5 | 349 | 25.7 | 3847 | 30.9 |
| Completed secondary education | 3341 | 37.8 | 5400 | 34.9 | 559 | 41.2 | 4095 | 32.9 |
| Tertiary education | 2579 | 29.2 | 4757 | 30.7 | 348 | 25.6 | 3708 | 29.8 |
| Missing | 495 | 5.6 | 1063 | 6.9 | 101 | 7.4 | 793 | 6.4 |
| Maternal occupational paint exposure data during pregnancy available | 8156 | 92.3 | 14568 | 94.1 | 1309 | 96.5 | 11859 | 95.3 |
| Paternal occupational paint exposure data around conception available | 8185 | 92.6 | 14210 | 91.8 | 1231 | 90.7 | 11392 | 91.6 |
| Occupational paint exposure data available for both parents | 7610 | 86.1 | 13421 | 86.7 | 1192 | 87.8 | 10901 | 87.6 |
1
Includes controls from all studies with ALL cases (that is, all studies except US, COG-E14).
2
Includes controls from all studies with AML cases (that is, all studies except Australia, Aus-ALL, Canada, Quebec and US, COG-E15).
3
All percentages have been rounded to one decimal place and thus the totals may range from 99.9%–100.1%
4
Age groups are based on the child’s age at the censoring date. For case, this was the date at diagnosis and for controls, it was the date that the study investigators nominated (either the date of recruitment or the date of the questionnaire return).