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. 2015 Oct 26;4(10):e002203. doi: 10.1161/JAHA.115.002203

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© 2015 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Effect of aspirin on oxylipids. Metabolites detected in our study samples are in bold. Metabolites significantly changed upon aspirin treatment are circled and color coded according to their percentage change upon aspirin treatment: red: change >−60%; orange: −60%> change >−25%; yellow: −25%> change >0%. COX indicates cyclooxygenase; CYP, cytochrome P‐450 monooxygenases; EpETrE, epoxyeicosatrienoic acid; LOX, lipoxygenases; TXA, thromboxane A2; PGH2: prostaglandin H2, PGF2: prostaglandin F2, PGFS: prostaglandin F synthase, PLA2: phospholipase A2.