Table 4.
In‐Hospital Bleeding and Mortality According to Various Bleeding Definitions
| Bleeding Definition Criteria Stratification | No. of Patients N=489 | Mortality | ||
|---|---|---|---|---|
| In‐Hospital N=16 | 30 Days N=28 | 1‐Year N=82 | ||
| No bleeding | 239 | 2 (0.8) | 5 (2.1) | 28 (14.2) |
| In‐hospital bleeding | 130 | 9 (6.9) | 14 (10.8) | 26 (23.4) |
| Periprocedural blood loss | 120 | 5 (4.2) | 9 (7.5) | 28 (25.2) |
| VARC‐2 | ||||
| VARC 2 (life‐threatening) | 60 | 8 (13.3) | 10 (16.7) | 16 (30.0) |
| VARC 2 (major) | 49 | 1 (2.0) | 4 (8.2) | 9 (20.2) |
| VARC 2 (minor) | 21 | 0 (0.0) | 0 (0.0) | 1 (7.7) |
| BARC | ||||
| BARC 5b | 2 | 2 (100.0) | 2 (0.0) | 2 (0.0) |
| BARC 3c | 1 | 0 (0.0) | 1 (27.0) | 1 (27.0) |
| BARC 3b | 57 | 6 (10.5) | 7 (12.3) | 13 (26.3) |
| BARC 3a | 48 | 1 (2.1) | 4 (8.3) | 9 (20.7) |
| BARC 2 | 22 | 0 (0.0) | 0 (0.0) | 1 (7.1) |
| TIMI | ||||
| TIMI (major) | 56 | 8 (14.3) | 9 (16.1) | 15 (30.2) |
| TIMI (minor) | 51 | 1 (2.0) | 5 (9.8) | 10 (21.6) |
| TIMI (minimal) | 23 | 0 (0.0) | 0 (0.0) | 1 (6.7) |
| GUSTO | ||||
| GUSTO (severe or life‐threatening) | 18 | 6 (33.3) | 7 (38.9) | 8 (46.5) |
| GUSTO (moderate) | 63 | 3 (4.8) | 5 (7.9) | 12 (22.1) |
| GUSTO (mild) | 49 | 0 (0.0) | 2 (4.2) | 6 (16.5) |
| Modified VARC | ||||
| Modified VARC (life‐threatening) | 84 | 13 (15.5) | 15 (17.9) | 27 (35.8) |
| Modified VARC (major) | 120 | 1 (0.8) | 7 (5.8) | 19 (17.5) |
| Modified VARC (minor) | 46 | 0 (0.0) | 1 (2.2) | 8 (23.5) |
Depicted are counts (cases over total for in‐hospital mortality and Kaplan–Meier incidence rates for 30 days and 1‐year mortality in %). BARC indicates Bleeding Academic Research Consortium; GUSTO, Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries investigators; TIMI, Thrombolysis in Myocardial Infarction investigators; VARC, Valve Academic Research Consortium.