Table 7.

Predictive Accuracy of Different Bleeding Definitions for 30‐Day Mortality

	VARC‐2 (LT)	BARC (Class ≥3)	BARC (Class ≥2)	TIMI (Major)	TIMI (Major+Minor)	GUSTO (Severe or LT)	GUSTO (Severe or LT and Moderate)	Modified VARC (LT)	BARC (Class ≥3) P Value	BARC (Class ≥2) P Value	TIMI (Major) P Value	TIMI (Major+Minor) P Value	GUSTO (Severe or LT) P Value	GUSTO (Severe or LT and Moderate) P Value	Modified VARC (LT)
Sensitivity	36%	50%	50%	32%	50%	25%	43%	54%	0.13	0.13	1.00	0.13	0.25	0.50	0.063
Specificity	89%	80%	75%	90%	80%	98%	85%	85%	<0.001	<0.001	0.25	<0.001	<0.001	0.001	<0.001
Accuracy	86%	78%	73%	87%	78%	93%	83%	83%	0.49	1.00	0.42	0.47	0.71	0.55	0.064

Data are percentages. Reference group for comparison of sensitivity, specificity: VARC2 LT. P value for Ho: equality of sensitivity/specificity. BARC indicates Bleeding Academic Research Consortium; GUSTO, Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries investigators; LT, life‐threatening; TIMI, Thrombolysis in Myocardial Infarction investigators; VARC, Valve Academic Research Consortium.