Table 2.
Study | Baseline TC, mmol/L (E/C) | Baseline LDL‐C, mmol/L (E/C) | Baseline HDL‐C, mmol/L (E/C) | Baseline TG, mmol/L (E/C) | Duration | Outcome Analysis | Design |
---|---|---|---|---|---|---|---|
Cooper et al, 198224 | 4.1 | — | — | 0.7 | 3 weeks | PP | CO |
Kestin et al, 198925 | 6.1 | 4.1 | 1.5 | 1.3 | 6 weeks | PP | CO |
Ling et al, 199226 | (5.6/5.5) | (3.7/3.6) | (1.3/1.3) | (1.3/1.0) | 4 weeks | PP | PL |
Nicholson et al, 199927 | (5.3/5.6) | — | (1.2/1.1) | (2.1/2.3) | 12 weeks | PP | PL |
Barnard et al, 200016 | 4.2 | 2.5 | 1.3 | 0.9 | 2 months | PP | CO |
Agren et al, 200118 | (4.6/5.2) | (3.0/3.5) | (1.2/1.2) | (1.0/1.0) | 3 months | PP | PL |
Burke et al, 200728 | (5.3/5.3) | — | — | (1.5/1.5) | 18 months | ITT | PL |
Elkan et al, 200829 | — | — | (1.4/1.3) | (1.1/1.1) | 12 months | PP | PL |
Barnard et al, 200919 | (4.8/5.2) | (2.7/3.0) | (1.4/1.3) | (1.7/1.8) | 74 weeks | ITT | PL |
Kahleova et al, 201130 | (4.4/4.2) | (2.5/2.6) | (1.1/1.1) | (2.1/2.1) | 12 weeks | ITT | PL |
Mishra et al, 201317 | (4.8/4.9) | (2.8/2.8) | (1.4/1.5) | (1.4/1.4) | 18 weeks | ITT | PL |
CO indicates crossover; E/C, experiment diet group/control diet group; HDL‐C, high‐density lipoprotein cholesterol; ITT, intention to treat; LDL‐C, low‐density lipoprotein cholesterol; PL, parallel; PP, per protocol; TC, total cholesterol; TG, triglyceride.