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Time course of hepatic transcriptional responses to dietary cholesterol supplementation. Mice were fed either chow or chow supplemented with 0.15% cholesterol for up to 1 week. Gene expression analysis was conducted at 0, 2.5, and 7 days. Analysis involved a total of 12 Mmp2 −/− mice and 12 WT mice (n=4 mice per time point). *P<0.05 vs WT. † P<0.05 vs 0 days on cholesterol. WT, wild type.
