Table 4.
Primary and Secondary Endpoints
| Usual Care | POC‐Troponin | P Value | P Adjusteda | |
|---|---|---|---|---|
| N | 296 | 305 | ||
| Intention‐to‐treat analysis | ||||
| Primary endpoint | ||||
| First medical contact to final disposition, hours | 9.1 (6.7, 11.2) | 8.8 (6.2, 10.8) | 0.050 | 0.059 |
| Discharged from ED | 9.3 (7.4, 11.0) | 8.9 (6.7, 10.6) | 0.035 | 0.034 |
| Admitted to hospital | 8.7 (5.4, 12.0) | 8.2 (4.9, 12.3) | 0.621 | 0.535 |
| Secondary endpoints within 30 days, n (%) | ||||
| All‐cause death | 4 (1.4) | 4 (1.3) | 0.966 | |
| ED visit | 34 (11.6) | 43 (14.2) | 0.338 | |
| Rehospitalization | 18 (6.1) | 21 (6.9) | 0.690 | |
| ED visit or rehospitalization | 47 (16.0) | 59 (19.5) | 0.265 | |
| Per protocol analysis | 294 | 252 | ||
| First medical contact to final disposition, hours | 9.1 (6.7, 11.2) | 8.9 (6.2, 10.8) | 0.069 | 0.074 |
| Discharged from ED | 9.3 (7.4, 11.00) | 8.9 (6.7, 10.2) | 0.021 | 0.017 |
| Admitted to hospital | 8.7 (5.4, 12.0) | 8.6 (5.3, 12.6) | 0.959 | 0.908 |
| Secondary endpoints within 30 days, n (%) | ||||
| All‐cause death | 4 (1.4) | 3 (1.2) | 0.861 | |
| ED visit | 34 (11.6) | 34 (13.6) | 0.493 | |
| Rehospitalization | 18 (6.2) | 17 (6.8) | 0.764 | |
| ED visit or rehospitalization | 47 (16.1) | 46 (18.4) | 0.478 | |
Values are median (25th–75th percentiles), unless otherwise stated. P values are nonparametric Mann–Whitney test. BP indicates blood pressure; ED, emergency department; POC, point‐of‐care.
a
Adjusted for modified GRACE score (age, heart rate, systolic BP, creatinine, cardiac arrest at admission, elevated cardiac enzymes, Killip class)