Distribution of bleeding risk scores and major bleeding events in the PRODIGY population. The Venn diagram (center) shows the patients included in the high bleeding risk category by each score. The ACUITY score had broader inclusion in the high‐risk category, whereas CRUSADE and HAS‐BLED were more restrictive (bottom right corner). Bleeding risk score distribution is presented for CRUSADE (top left corner), ACUITY (top right corner), and HAS‐BLED (bottom left corner), with the number of patients with major bleeding in the high‐risk category (gray section) and in the low‐ to intermediate‐risk category according to 3 bleeding definitions. ACUITY indicates Acute Catheterization and Urgent Intervention Triage Strategy; BARC, Bleeding Academic Research Consortium; CRUSADE, Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Implementation of the ACC/AHA Guidelines; GUSTO, Global Use of Strategies to Open Occluded Arteries; HAS‐BLED, Hypertension, Abnormal Renal/Liver Function, Stroke, Bleeding History or Predisposition, Labile INR, Elderly, Drugs/Alcohol Concomitantly; PRODIGY, Prolonging Dual Antiplatelet Treatment After Grading Stent‐Induced Intimal Hyperplasia Study; TIMI, Thrombolysis in Myocardial Infarction.