Table 3.

Relation Between Chemokines and Vascular Characteristics (n=124)

	Common CIMT (mm)a	P Value	Common Carotid Distensibility (MPA−1)a	P Value	Common Carotid YEM (kPa)a	P Value
MCP‐1
Crude modelb	0.50 (−1.19, 2.22)	0.55	1.92 (−2.47, 6.50)	0.40	−2.37 (−7.13, 2.63)	0.34
Model 1b	0.50 (−1.19, 2.22)	0.57	2.63 (−1.69, 7.25)	0.24	−3.34 (−7.96, 1.51)	0.17
Model 2b	0.70 (−−1.09, 2.53)	0.44	−0.60 (−5.07, 3.98)	0.79	−0.30 (−5.45, 5.13)	0.90
RANTES
Crude modelb	−0.60 (−2.27, 1.11)	0.51	−3.25 (−7.23, 0.90)	0.13	2.74 (−2.08, 7.79)	0.27
Model 1b	−0.60 (−2.27, 1.21)	0.52	−4.30 (−8.24, −0.20)	0.04c	4.19 (−0.70, 9.31)	0.09
Model 2b	−0.70 (−2.47, 1.21)	0.48	−5.45 (−9.43, −1.39)	0.01c	5.55 (0.40, 10.85)	0.03c
VCAM
Crude modelb	−0.03 (−1.69, 1.71)	0.97	−3.54 (−7.50, 0.70)	0.10	3.66 (−1.19, 8.87)	0.14
Model 1b	−0.03 (−1.78, 1.71)	0.97	−3.54 (−7.50, 0.60)	0.10	3.67 (−1.09, 8.76)	0.13
Model 2b	−0.50 (−2.18, 1.21)	0.57	−1.88 (−6.01, 2.33)	0.36	2.33 (−2.46, 7.47)	0.35
ICAM
Crude modelb	0.80 (−0.90, 2.53)	0.34	−0.60 (−4.88, 3.98)	0.80	−0.40 (−5.35, 4.71)	0.87
Model 1b	0.90 (−0.90, 2.63)	0.33	−1.00 (−5.26, 3.56)	0.67	0.10 (−4.78, 5.23)	0.97
Model 2b	0.02 (−1.78, 1.92)	0.98	−1.19 (−5.54, 3.36)	0.60	1.21 (−4.02, 6.61)	0.65

BMI indicates body mass index; CIMT, carotid intima‐media thickness; HDL, high‐density lipoprotein; HOMA‐IR, homeostasis model assessment of insulin resistance; ICAM, intracellular adhesion molecule; LDL, low‐density lipoprotein; MCP‐1, monocyte chemotactic protein 1; RANTES, regulated on activation normal T‐cell expressed and secreted; SBP, systolic blood pressure; VCAM, vascular cell adhesion molecule; YEM, Young's Elastic Modulus.

^aValues are regression coefficients per 1 SD increase in chemokine level with 95% confidence intervals.

^bCrude model, model 1: adjusted for sex; model 2: adjusted for sex, SBP, BMI, LDL‐cholesterol level, HDL‐cholesterol level, triglyceride level and HOMA‐IR.

^c P<0.05.