Fig. 1.
Ca2+ dependence of a Ca2+-activated Cl− channel from toad olfactory cilia. a Isolated olfactory receptor neuron under DIC optics; s, soma; d, dendrite; k, dendritic knob; c, cilia; p, patch-clamp pipette. b Cl− currents from an inside-out excised ciliary patch at different Ca2+ concentrations (Vm = −30 mV, Vbath − Vpipette); whole-point amplitude histograms are shown by each trace. c Plot of nPo vs. [Ca2+] (nPo: number of channels times the open probability; see “Methods” section). The data point are fit with a Hill function; K0.5 = 0.38 µM, n = 2.7 (N = 4)