Table 2.
Hemodynamic, respiratory and oxygenation parameters during each mode of ventilation at each time point in the ARDS group (n = 8)
| Ventilation mode | Pre-hemorrhage mean ± SD | Hemorrhage mean ± SD | Retransfusion mean ± SD | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ventilation mode: | ||||||||||||
| VT:ml.kg-1 | VT:10 | VT:6 | VT:6 | Average across variants of ventilation | VT:10 | VT:6 | VT:6 | Average across variants of ventilation | VT:10 | VT:6 | VT:6 | Average across variants of ventilation |
| RR: breaths/min | RR: 15 | RR: 25 | RR: 15 | RR: 15 | RR: 25 | RR: 15 | RR: 15 | RR: 25 | RR: 15 | |||
| Cardiac output (l.min-1) | 6.7 ± 1.3 | 6.8 ± 1.5 | 7.6 ± 1.4 | 7.0 ± 1.4 | 3.6 ± 0.9 | 3.4 ± 0.8 | 4.5 ± 1.0 | 3.8 ± 1.0 | 6.9 ± 3.0 | 7.4 ± 2.6 | 8.2 ± 2.1 | 7.5 ± 2.5 |
| Heart rate (bpm) | 145 ± 18 | 157 ± 30 | 171 ± 36 | 158 ± 30 | 210 ± 24 | 215 ± 17 | 209 ± 29 | 212 ± 22 | 172 ± 32 | 170 ± 27 | 181 ± 24 | 174 ± 27 |
| Mean arterial pressure (mmHg) | 77 ± 19 | 87 ± 14 | 88 ± 13 | 84.0 ± 16.0 | 51 ± 13 | 67 ± 16 | 67 ± 12 | 62 ± 15 | 79 ± 10 | 85 ± 10 | 84 ± 12 | 83 ± 11 |
| Central venous pressure (mmHg) | 8 ± 2 | 7 ± 2 | 7 ± 2 | 8 ± 2 | 6 ± 2 | 5 ± 1 | 5 ± 2 | 5 ± 1 | 9 ± 1 | 8 ± 1 | 8 ± 1 | 9 ± 1 |
| Shunt (%) | 26 ± 15 | 41 ± 12 | 45 ± 15 | 37 ± 16 | 6 ± 7 | 8 ± 6 | 11 ± 9 | 9 ± 7 | 16 ± 17 | 20 ± 16 | 27 ± 19 | 20 ± 18 |
| PaO2:FiO2 (mmHg) | 105 ± 38 | 76 ± 20 | 75 ± 19 | 85 ± 30 | 218 ± 105 | 201 ± 95 | 177 ± 80 | 199 ± 91 | 207 ± 125 | 157 ± 77 | 133 ± 59 | 166 ± 93 |
| SVO2 (%) | 69 ± 11 | 70 ± 9 | 69 ± 11 | 69 ± 10 | 59 ± 14 | 67 ± 15 | 67 ± 17 | 64 ± 15 | 79 ± 7 | 79 ± 8 | 81 ± 8 | 80 ± 7 |
| Global oxygen delivery (ml.min-1.m-2) | 731 ± 146 | 701 ± 219 | 798 ± 265 | 744 ± 210 | 408 ± 113 | 369 ± 114 | 501 ± 160 | 427 ± 137 | 740 ± 392 | 846 ± 404 | 961 ± 323 | 849 ± 370 |
| Arterial content in oxygen (ml.dl-1) | 11.0 ± 0.9 | 10.2 ± 1.5 | 10.4 ± 1.7 | 10.5 ± 1.4 | 10.9 ± 1.3 | 10.9 ± 1.5 | 11.0 ± 1.5 | 11.0 ± 1.4 | 11.5 ± 1.0 | 11.2 ± 1.6 | 11.6 ± 1.1 | 11.4 ± 1.2 |
| Hemoglobin (g.dl-1) | 8.4 ± 0.4 | 8.4 ± 0.6 | 8.6 ± 0.8 | 8.5 ± 0.6 | 7.6 ± 0.6 | 7.7 ± 0.8 | 7.9 ± 0.7 | 7.8 ± 0.7 | 8.1 ± 1.0 | 8.1 ± 1.3 | 8.6 ± 0.8 | 8.3 ± 1.0 |
| SaO2 (%) | 92 ± 7 | 86 ± 8 | 85 ± 8 | 87 ± 8 | 97 ± 4 | 96 ± 4 | 95 ± 6 | 96 ± 5 | 97 ± 4 | 95 ± 4 | 94 ± 6 | 95 ± 5 |
| Respiratory sytem compliance (ml.cm H2O−1) | 16.4 ± 3.0 | 17.6 ± 3.9 | 16.0 ± 2.6 | 16.8 ± 3.2 | 21.5 ± 2.9 | 22.5 ± 4.6 | 21.2 ± 4.3 | 21.9 ± 4 | 18.7 ± 2.7 | 19.4 ± 5.2 | 17.3 ± 2.9 | 18.5 ± 3.9 |