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. Author manuscript; available in PMC: 2016 Jun 16.
Published in final edited form as: Nature. 2015 Dec 16;528(7583):580–584. doi: 10.1038/nature16162

Figure 4. Crystal structures of fifteen designs are in close agreement with the design models.

Figure 4

Crystal structures are in yellow, and the design models in grey. Insets in circles show the overall shape of the repeat protein. The RMSD values across all backbone heavy atoms are: 1.50 Å (DHR4), 1.73 Å (DHR5), 1.30 Å (DHR7), 2.28 Å (DHR8), 1.79 Å (DHR10), 2.38 Å (DHR14), 1.21 Å (DHR18), 0.87 Å (DHR49), 1.33 Å (DHR53), 0.93 Å (DHR54), 1.54 Å (DHR64), 0.67 Å (DHR71), 1.73 Å (DHR76), 1.04 Å (DHR79), 0.65 Å (DHR81). Hydrophobic side chains in the crystal structures (in red) are largely captured by the designs (Extended Data Fig. 5).