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. Author manuscript; available in PMC: 2016 Apr 26.
Published in final edited form as: J Am Chem Soc. 2015 Apr 22;137(17):5741–5747. doi: 10.1021/ja513117p

Figure 4.

Figure 4

Overview of the cellular sensing pathways leading to the activation of NHEJ and HR repair, the two canonical pathways that ameliorate DNA DSBs. Only factors relevant to the present study are shown; for detailed discussions, see ref 8.