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. Author manuscript; available in PMC: 2016 Oct 22.
Published in final edited form as: Science. 2016 Mar 31;352(6284):467–470. doi: 10.1126/science.aaf5316

Fig. 2. The structures of Zika virus E and M proteins.

Fig. 2

A) The E protein dimer is shown in ribbon form viewed down the two-fold axis. The color code fits the standard designation of E protein domains I (red), domain II (yellow) and domain III (blue). The underlying stem and transmembrane residues are shown (pink). The fusion loop (green; Fig. S1), Asn154 glycan, and the variable loop surrounding the Asn154 glycan (residues 145–160, cyan) are highlighted. B) Side view of the E-M dimer showing the three E ectodomains as well as the E stem/transmembrane domains (pink) and the M loop and stem/transmembrane domains (light blue). The E and M transmembrane domains are found within the lipid bilayer (Fig. 1C). All residues of M (1–75) and all but three residues of E (1–501) were identified in the density. The Asn154 glycan from one monomer is labeled and can be seen projecting from the surface.