Table 6.

Variables Predicting Survival in Patients with HP

	Unadjusted (n=120)			Adjusted* (n=118)
Characteristic	HR	p-value	95% CI	HR	p-value	95% CI
Autoimmune disease or features (HPAF)	1.28	0.591	0.53 – 3.10	4.45	0.010	1.43 – 13.88
Age	1.02	0.184	0.99 – 1.06	1.00	0.893	0.95 – 1.05
Gender	1.09	0.798	0.55 – 2.17	1.73	0.151	0.82 – 3.65
Caucasian race	8.42	0.036	1.15 – 61.68	9.33	0.037	1.14 – 76.30
BMI	0.95	0.034	0.90 – 0.99	0.95	0.076	0.89 – 1.01
Digital clubbing	3.47	<0.001	1.77 – 6.81	1.34	0.469	0.60 – 2.99
HRCT fibrosis score	1.04	<0.001	1.02 – 1.05	1.02	0.045	1.00 – 1.04
FVC@ (% predicted)	0.94	<0.001	0.92 – 0.97	0.97	0.059	0.94 – 1.00
DLCO (% predicted)	0.96	<0.001	0.95 – 0.98	0.99	0.489	0.97 – 1.01
Oxygen therapy	4.38	0.001	1.81 – 10.59	2.51	0.094	0.85 – 7.38

^*Adjusted for all variables listed above;

^@n=119;

HP = Hypersensitivity Pneumonitis; HPAF= Hypersensitivity Pneumonitis with Autoimmune features as defined in the text;