Table 6.
Unadjusted (n=120) |
Adjusted* (n=118) |
|||||
---|---|---|---|---|---|---|
Characteristic | HR | p-value | 95% CI | HR | p-value | 95% CI |
Autoimmune disease or features (HPAF) | 1.28 | 0.591 | 0.53 – 3.10 | 4.45 | 0.010 | 1.43 – 13.88 |
Age | 1.02 | 0.184 | 0.99 – 1.06 | 1.00 | 0.893 | 0.95 – 1.05 |
Gender | 1.09 | 0.798 | 0.55 – 2.17 | 1.73 | 0.151 | 0.82 – 3.65 |
Caucasian race | 8.42 | 0.036 | 1.15 – 61.68 | 9.33 | 0.037 | 1.14 – 76.30 |
BMI | 0.95 | 0.034 | 0.90 – 0.99 | 0.95 | 0.076 | 0.89 – 1.01 |
Digital clubbing | 3.47 | <0.001 | 1.77 – 6.81 | 1.34 | 0.469 | 0.60 – 2.99 |
HRCT fibrosis score | 1.04 | <0.001 | 1.02 – 1.05 | 1.02 | 0.045 | 1.00 – 1.04 |
FVC@ (% predicted) | 0.94 | <0.001 | 0.92 – 0.97 | 0.97 | 0.059 | 0.94 – 1.00 |
DLCO (% predicted) | 0.96 | <0.001 | 0.95 – 0.98 | 0.99 | 0.489 | 0.97 – 1.01 |
Oxygen therapy | 4.38 | 0.001 | 1.81 – 10.59 | 2.51 | 0.094 | 0.85 – 7.38 |
Adjusted for all variables listed above;
n=119;
HP = Hypersensitivity Pneumonitis; HPAF= Hypersensitivity Pneumonitis with Autoimmune features as defined in the text;