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. 2016 Mar 1;62(10):1235–1241. doi: 10.1093/cid/ciw112

Table 4.

Detection of Interferon Gamma in Blood Samples From Patients With Early Lyme Disease Collected Pretreatment or 2 Months Posttreatment With Doxycycline

Subject Levels (IU/mL) of IFN-γ in Blood Samples Collecteda
Pretreatment 2 mo Posttreatment
1 1.16b 0
2 0 0.06
3 5.03b 0
4 0 0
5 0 0
6 3.86b 2.61b
7 1.82b 0.16
8 0.45b 0.02
9 1.69b 1.59b
10 0.78b 0.46b
11 0.49b 0.12
12 0.29 0
13 0.33b 0
14 0 0
15 2.58b 0
16 2.02b 0.11
17 0 0
18 10.61b 1.12b
19 0.42b 0
20 0 0.12
21 0 0
22 2.29b NT
23 4.99b 0.21
24 0.75b 0.27
25 0.43b NT
26 0.47b 0.20
27 0.82b 0.30
28 0.66b 0.05
29 0.30 0

Abbreviations: IFN-γ, interferon gamma; NT, not tested.

a Values displayed are the IFN-γ value obtained from peptide stimulation of whole blood samples minus nil tube reactivity (Supplementary Table 2).

b Results are ≥3 standard deviations above the mean value (≥0.33 IU/mL) of normal (n = 187) and anaplasmosis (n = 5) sera.