TABLE 3.
Change in Height in Siblings With CH Over the Course of L-thyroxine Treatment
| Visits | Patient 1 | Patient 2 | Patient 3 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age (y) | Height SD | Height (cm) | Δ Height (SDS) | Age (y) | Height SD | Height (cm) | Δ Height (SDS) | Age (y) | Height SD | Height (cm) | Δ Height (SDS) | |
| Initial | 14.8 | –7.5 | 89.1 | N/A | 7.7 | −8.1 | 84 | N/A | 0.5 | –8.1 | 52.2 | N/A |
| Year 1 | 15.8 | –7.4 | 93.1 | 0.1 | 8.7 | −6.2 | 98.2 | 1.9 | 1.5 | –2.9 | 73 | 5.2 |
| Year 2 | 16.7 | –8.3 | 99.8 | –0.9 | 9.6 | −4.9 | 107 | 1.3 | 2.4 | –2.3 | 82.3 | 0.6 |
| Year 3 | 17.8 | –8.7 | 107.7 | –0.4 | 10.7 | −3.8 | 116 | 1.1 | 3.6 | –2.2 | 91.1 | 0.1 |
| Year 4 | 18.9 | –8.1 | 116.0 | 0.6 | 11.8 | −4.1 | 125.2 | −0.3 | 4.6 | –1.9 | 98 | 0.3 |
| Year 5 | 19.4 | –8.0 | 117.5 | 0.1 | 12.3 | −4.1 | 128.0 | 0.0 | 5.1 | –1.7 | 101.5 | 0.2 |
| Year 6 | 20.6a | –6.9 | 126.5 | 1.1 | 13.6 | −3.5 | 136.7 | 0.6 | 6.4 | –1.4 | 110 | 0.3 |
| Year 7 | 21.5 | –6.1 | 134.4 | 0.8 | 14.4 | −2.9 | 142.2 | 0.6 | 7.2 | –1.5 | 115.9 | −0.1 |
| Year 8 | 22.0 | –5.2 | 136.0 | 0.9 | 15.0 | −2.07 | 148.6 | 0.83 | 8.0 | –1.3 | 120.6 | 0.2 |
N/A, not applicable; SDS, SD score.
a
Growth hormone therapy was started