Table 1.
Baseline Demographics and Clinical Characteristics of the 128 Patients
| Variable | Value |
|---|---|
| Center, No. (%) | |
| Columbia University Medical Center | 18 (14.1) |
| UCLA | 9 (7.0) |
| Washington University in St Louis | 18 (14.1) |
| Massachusetts General Hospital | 27 (21.1) |
| University of Arkansas for Medical Sciences | 16 (12.5) |
| Cleveland Clinic Foundation | 9 (7.0) |
| Hospital of the University of Pennsylvania | 5 (3.9) |
| University of Oklahoma | 4 (3.1) |
| Tulane University | 16 (12.5) |
| The University of Alabama at Birmingham | 6 (4.7) |
| Age, median (range), y | 74 (23–99) |
| Male sex, No. (%) | 65 (50.8) |
| Race/ethnicity, No. (%) | |
| White | 81 (63.2) |
| African American | 38 (29.7) |
| Hispanic | 7 (5.5) |
| Other | 2 (1.6) |
| Hypertension, No. (%) | 106 (82.8) |
| Diabetes mellitus, No. (%) | 38 (29.7) |
| Hyperlipidemia, No. (%) | 68 (53.3) |
| Prior stroke, No. (%) | 39 (30.5) |
| NIHSS score, median (range) | 15 (0–33) |
| ASPECTS score, median (range) | 10 (5–10) |
| Neurointerventional procedure, No. (%) | 18 (14.1) |
| Stroke subtype, No. (%) | |
| Small-vessel disease | 5 (4.1) |
| Large-vessel disease | 11 (9.0) |
| Cardioembolic | 57 (46.7) |
| Cryptogenic | 13 (10.7) |
| Other | 12 (9.8) |
| Hematoma volume, median (range), mL | 25 (1–245) |
| Time from initiation of rtPA therapy to sICH diagnosis, median (range), min | 470 (30–2572) |
| Time from sICH diagnosis to treatment of sICH, median (range), min | 112 (12–628) |
| Type of treatment, No. (%) | |
| Any treatment | 49 (38.2) |
| Fresh frozen plasma | 26 (20.3) |
| Vitamin K | 7 (5.5) |
| Cryoprecipitate | 40 (31.3) |
| Platelet transfusion | 37 (28.9) |
| Aminocaproic acid | 2 (1.6) |
| Prothrombin complex concentrate | 3 (2.3) |
| Recombinant factor VIIa | 3 (2.3) |
| Surgical decompressive craniotomy or hematoma evacuation | 18 (14.6) |
| Code status change to comfort measures in the first 24 h, No. (%) | 37 (28.9) |
| Hematoma expansion after diagnosis, No. (%) | 22 (26.8) |
| In-hospital mortality, No. (%) | 67 (52.3) |
Abbreviations: ASPECTS, Alberta Stroke Program Early CT [Computed Tomographic] Score; NIHSS, National Institutes of Health Stroke Scale; rtPA, recombinant tissue plasminogen activator; sICH, symptomatic intracerebral hemorrhage; UCLA, University of California, Los Angeles.