Table 1.
Body and liver weight in growing GH-overexpressing mice and normal littermates.
| 2w N | 2w T | 4w N | 4w T | 9w N | 9w T | |
|---|---|---|---|---|---|---|
| BW (g) | 7.5 ± 0.2(a) | 7.5 ± 0.4(A) | 15.3 ± 0.7(b) | 21.9 ± 0.9(B*) | 23.7 ± 1.2(c) | 39.4 ± 1.7(C*) |
| BW ratio for T/N | 0.98 ± 0.05(A) | 1.45 ± 0.09(B) | 1.56 ± 0.09(B) | |||
| LW (g) | 0.22 ± 0.01(a) | 0.27 ± 0.03(A) | 0.94 ± 0.07(b) | 1.62 ± 0.06(B*) | 1.23 ± 0.09(b) | 3.15 ± 0.14(C*) |
| LW ratio for T/N | 1.23 ± 0.07(A) | 1.75 ± 0.20(B) | 2.57 ± 0.14(C) | |||
| LW/BW(%) | 2.9 ± 0.1(a) | 3.6 ± 0.2(A) | 6.1 ± 0.2(b) | 7.4 ± 0.2(B*) | 5.4 ± 0.2(b) | 8.1 ± 0.1(C*) |
| LW/BW ratio for T/N | – | 1.16 ± 0.05(A) | – | 1.23 ± 0.14(A) | – | 1.57 ± 0.68(B) |
Body (BW) and liver weight (LW) of GH-transgenic animals (T) and their non-transgenic littermates (N) was assessed for 2-week-old (2w), 4-week-old (4w) and 9-week-old (9w) mice. Data are presented as mean value ± SEM (n = 8). Different letters denote significant difference by age; small letters correspond to normal mice and capital letters to transgenic animals. Asterisks indicate significant difference between GH-overexpressing animals and their corresponding non-transgenic age controls. Ratios are calculated from individual values and not from the averages in the table, which may account for discrepancies observed.