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Ixekizumab binds specifically to IL-17A.
Notes: Human IL-17 family member proteins, mouse IL-17A, and human IL-22 were coated into individual ELISA plate wells. Ixekizumab was then added at varying concentration up to 10 µg/mL. The absorbance at 450 nm represents the average values and standard error obtained from duplicate determinations at each concentration of ixekizumab bound to the test proteins.
Abbreviations: ELISA, enzyme-linked immunosorbent assay; IL, interleukin.
