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Loss of organized cell-cell junctions in α3 integrin-silenced cells. Integrin α3 was silenced with 2 different shRNA constructs in E-cadherin-GFP-expressing A431 cells. The α3 silenced cells and parental A431 cells expressing E-cadherin-GFP (green) were fixed and stained for α3 integrin (red). DAPI-stained nuclei are shown in blue in the overlay image.
