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A function-blocking anti-α3 integrin antibody perturbs cell junctions. Parental A431 cells expressing E-cadherin-GFP (green) were left untreated (A–C), or treated overnight with function blocking antibodies recognizing α3 integrin (D-F) or α2 integrin (G–I). Cells were fixed and stained for actin (magenta). Antibodies used were A3-IIF5 (anti-α3) and A2-IIE10 (anti-α2).
