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Relationship between methylation of BDNF rs6265 in PBMCs and hOCs exposure in healthy humans. Boxplot of rs6265 methylation (T scores) as a function of hOCs exposure: Val/Val homozygotes (N = 110) exposed to hOCs have greater methylation compared with ValVal not exposed, while Val/Met subjects (N = 59) exposed have reduced methylation compared with ValMet not exposed. See text and Supplemental file 1 for statistics.
