Skip to main content
. 2016 Feb 18;11(1):11–23. doi: 10.1080/15592294.2015.1117736

Figure 5.

Figure 5.

BDNF rs6265 methylation in PBMCs and schizophrenia risk. a: Bargraph (mean ± s.e.m.) of rs6265 methylation (T scores) in healthy subjects (168 ValVal, 77 ValMet), patients with schizophrenia (122 ValVal, 40 ValMet), siblings (97 ValVal, 43 ValMet), parents of patients (148 ValVal, 69 ValMet): in ValVal subjects, rs6265 methylation is lower in healthy subjects, compared with siblings, parents and patients with schizophrenia. In ValMet subjects, rs6265 methylation is greater in healthy subjects, compared with siblings and parents of patients, while it is not significantly different compared with patients. b: Bargraph (mean + s.e.m.) of the effect of treatment with haloperidol 1 μM for 2 and 5 hours on rs6265 methylation changes in PBMCs of ValVal (N = 11) and ValMets (N = 6). See text and Supplemental file 1 for statistics.