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mRNA expression level of proapoptotic Bcl-2 family members. Cells were treated with 50 μM of Sirtinol, 4 μM of SAHA and 4 μM of 5b and were incubated for 24 h. (A, B) RT-PCR analysis of different members of the family indicating the level of mRNA expression after treatment. (C, D) Histograms represent relative expression of gene levels to internal control GAPDH. Plots are mean values from 3 independent experiments. Error bars represent standard deviation.
