Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jul 20;16(10):1486–1501. doi: 10.1080/15384047.2015.1071731

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Taylor & Francis Group, LLC

PMC Copyright notice

Figure 7. — Effect of 5b on histone acetylation and methylation. (A) Treatment with 5b at 4, 8 μM concentrations for 24 h in MCF-7 and MDA-MB-231 cells significantly induced the level of acetylated histone H4 as compared to DMSO (0.1%) control. (B, C) Immunofluorescence studies with anti-acetyl histone H4 antibody on cells treated with 5b showed profound expression of acetylated histone H4. (D, F) Metaphase spreads isolated from MCF-7 and MDA-MB-231 cells treated with SAHA and 5b at 4 μM concentration for 24 h and control untreated cells hybridized with histone H3K14ac antibody. (E, G) Percentage of H3K14ac foci is shown. Error bar represents standard deviation from 3 different experiments. Bars with * are significantly different from all the other groups at p ≤ 0.01.