Table 4.
Diagnostic performance for active IBD lesion on DWI and gadolinium using endoscopic or surgery findings as gold standard in patient-level analysis, overall and by bowel segments
| DWI and gadolinium results | Sensitivity | Specificity | PPV | NPV | Accuracy |
|---|---|---|---|---|---|
| DWI results | |||||
| All segments | 88.1 (37/42)a | 83.3 (5/6) | 97.4 (37/38) | 50.0 (5/10) | 87.5 (42/48) |
| Jejunum | 0.0 (0/1) | 100.0 (47/47) | – | 97.9 (47/48) | 97.9 (47/48) |
| Ileum | 66.7 (2/3) | 93.3 (42/45) | 40.0 (2/5) | 97.7 (42/43) | 91.7 (44/58) |
| Terminal ileum and ileo-caecal junction | 79.0 (15/19) | 93.1 (27/29) | 88.2 (15/17) | 87.1 (27/31) | 87.5 (42/48) |
| Ascending colon | 47.4 (9/19) | 96.6 (28/29) | 90.0 (9/10) | 73.7 (28/38) | 77.1 (37/48) |
| Transverse colon | 41.2 (7/17) | 96.8 (30/31) | 87.5 (7/8) | 75.0 (30/40) | 77.1 (37/48) |
| Descending colon | 59.1 (13/22) | 100.0 (26/26) | 100.0 (13/13) | 74.3 (26/35) | 81.2 (39/48) |
| Rectosigmoid colon | 63.0 (17/27) | 100.0 (21/21) | 100.0 (17/17) | 67.7 (21/31) | 79.2 (38/48) |
| Gadolinium results | |||||
| All segments | 66.7 (28/42) | 83.3 (5/6) | 96.6 (28/29) | 26.3 (5/19) | 68.7 (33/48) |
| Jejunum | 0.0 (0/1) | 100.0 (47/47) | – | 97.9 (47/48) | 97.9 (47/48) |
| Ileum | 66.7 (2/3) | 93.3 (42/45) | 40.0 (2/5) | 97.7 (42/43) | 91.7 (44/48) |
| Terminal ileum and ileocaecal junction | 63.2 (12/19) | 96.6 (28/29) | 92.3 (12/13) | 80.0 (28/35) | 83.3 (40/48) |
| Ascending colon | 42.1 (8/19) | 100.0 (29/29) | 100.0 (8/8) | 72.5 (29/40) | 77.1 (37/48) |
| Transverse colon | 35.3 (6/17) | 100.0 (31/31) | 100.0 (6/6) | 73.8 (31/42) | 77.1 (37/48) |
| Descending colon | 40.9 (9/22) | 100.0 (26/26) | 100.0 (9/9) | 66.7 (26/39) | 72.9 (35/48) |
| Rectosigmoid colon | 44.4 (12/27) | 100.0 (21/21) | 100.0 (12/12) | 58.3 (21/36) | 68.7 (33/48) |
DWI, diffusion weighted imaging; IBD, inflammatory bowel disease; NPV, negative-predictive value; PPV, positive-predictive value.
Values are percentage (numbers).
a
p < 0.05 for comparison with sensitivity of gadolinium by exact McNemar's test.