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. Author manuscript; available in PMC: 2016 Apr 26.
Published in final edited form as: Pharmacogenomics J. 2011 Aug 9;12(5):446–452. doi: 10.1038/tpj.2011.35

Figure 3. Empirical Significance of Combined Models.

Figure 3

Empirical significance of the interaction models is displayed as a Q-Q plot. The maximum negative log p-value is 3.0 due to a maximum of 1,000 permutations performed. There is a clear deviation from the expected distribution of p-values (line of identity) across most of the interaction models.