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. 2015 Oct 26;6:8688. doi: 10.1038/ncomms9688

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(a) Representative EEG traces of a rAAV-Venus- and rAAV-MTF1ΔC-Venus-injected animal 5 min after pilocarpine application and 5, 20 and 40 min after SE onset. (b) No differences for the latency to first seizure (left) and latency to SE (right) in animals injected with rAAV-MTF1ΔC-Venus (n=7) compared with animals injected with rAAV-Venus (n=5). (c) Representative EEG recordings from SE-experienced rAAV-Venus- and rAAV-MTF1ΔC-Venus-injected animals. (d) Average number of seizures in the chronic epileptic stage in rAAV-Venus- (n=5) and rAAV-MTF1ΔC-Venus-injected animals (n=7; t-test: **P≤0.01). (e) Spontaneous seizure activity after SE in rAAV-Venus versus rAAV-MTF1ΔC-Venus animals. The frequency of spontaneous seizures is significantly decreased in rAAV-MTF1ΔC-Venus (n=5) versus rAAV-Venus animals (n=7; t-test: *P≤0.05).