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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Psychopharmacology (Berl). 2016 Jan 23;233(10):1867–1877. doi: 10.1007/s00213-016-4211-3

Figure 5.

Figure 5

Effect of AM404 on cocaine self-administration in squirrel monkeys under a fixed-ratio 10 (FR10) schedule. Number of cocaine injections per 1-h session (a), overall response rates in the presence of the green light signaling cocaine availability (b) and total cocaine intake per session (c) are shown as a function of the cocaine dose (abscissae log scale) after vehicle or AM404 (0.3 mg/kg) pretreatment. Each data point represents the mean ± SEM of the last three sessions under each cocaine and vehicle (V) conditions (n=3).