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. Author manuscript; available in PMC: 2016 Sep 28.
Published in final edited form as: Nat Neurosci. 2016 Mar 28;19(5):734–741. doi: 10.1038/nn.4274

Figure 6.

Figure 6

Npy1RMeA neurons that project to the pBNST evoke territorialism. (a) Unilateral injection of AAV-DIO-ChR2:YFP into the MeA of Npy1rCre mice, with ipsilateral optic cannulas implanted above the pBNST or the VMH. (b) Stimulation of NpyRMeA fibers over pBNST increased aggression in a home-cage intruder assay (left panel), while stimulation of fibers over VMH does not (right panel); assessed during the dark cycle (17:00 – 19:00) and compared using paired two-tailed Student's t-tests. (c) Neither VMH nor pBNST-projecting Npy1RMeA cells decreased feeding (recorded from 17:00 – 21:00); compared using paired two-tailed Student's t-tests. Stimulation paradigm (472 nm, 10 mW power at the tip): 10 Hz with 5-ms pulses that continue for 5 s followed by 2 s light-off recovery. See methods for detailed statistics.