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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: J Mol Cell Cardiol. 2015 Dec 1;93:73–83. doi: 10.1016/j.yjmcc.2015.11.020

Figure 1. Electrical Behavior of Fibroblasts.

Figure 1

(A) The MacCannell model predicts myocyte action potential duration and fibroblast potential elevation are shortened as the number of fibroblasts connected to myocytes is increased. Figure adapted with permission by Biophysical Journal from MacCannell et al 2007 [24]. (B) Predictions from the Ashihara model show that increased numbers of fibroblasts connected to a myocyte can slow conduction (dashed arrow) or even cause conduction block (double lines). Figure adapted with permission by Circulation Research from Ashihara et al 2012 [37].