A) Arginine and proline metabolism pathway supplies fibrillary collagen synthesis. Normalized intensity of metabolites B) L-Argininosuccinate, C) L-Citruline, D) L-Arginine, E) L-Hydroxyproline, F) L-Proline, and G) L-Hydroxyarginine for all groups. * denotes significance by one-way ANOVA with Tukey’s post hoc analysis (p < 0.05). Mean ± SD, n = 5