Table 3.
Associations of sirolimus with non-cancer causes of death
| Hazard ratio comparing sirolimus users to non-users (95% confidence interval) |
||
|---|---|---|
| Cause of death | Unadjusted | Adjusteda |
| Graft failure | 1.78 (0.98–3.23) | 1.80 (0.93–3.48) |
| Infection | 0.39 (0.10–1.57) | 0.41 (0.10–1.70) |
| Cardiovascular disease | 1.00 (0.31–3.20) | 1.18 (0.35–3.95) |
a
Models are adjusted for ethnicity, calendar year of transplant, total tumor volume, AFP, allocated MELD score, calculated MELD score, transplant center size, and use of IL-2 induction therapy.