Table 3.
Polysomnographic and cardiovascular variables of subjects in the comorbid and healthy group
| Comorbid group (n=370)
|
P | Healthy group (n=101)
|
P | |||||
|---|---|---|---|---|---|---|---|---|
| Normal (n=171) | Mild-to-moderate (n=103) | Severe (n=96) | Normal (n=55) | Mild-to-moderate (n=24) | Severe (n=22) | |||
| Age (yr) | 68.1 (5.65) | 67.67 (5.46) | 67.95 (5.95) | 0.832 | 67.45 (5.49) | 67.58 (5.44) | 69.32 (4.62) | 0.363 |
| $ Male (%) | 48 (28.1) | 67 (65.0) | 73 (76.0) | <0.001 * | 18 (34.5) | 10 (41.7) | 12 (54.5) | 0.204 |
| BMI (kg/m2) | 23.39 (2.42) | 24.51 (2.78) | 25.84 (3.13) | <0.001 * | 22.85 (2.6) | 24.08 (2.85) | 23.85 (2.89) | 0.124 |
| PSQI | 6.68 (3.82) | 7.08 (3.71) | 6.99 (3.82) | 0.044 * | 7.29 (3.82) | 6.42 (3.96) | 7.52 (4.25) | 0.583 |
| ESS | 6.35 (3.87) | 7.57 (4.13) | 8.32 (5.63) | 0.144 | 6.98 (4.7) | 6.79 (4.78) | 9.05 (4.51) | 0.187 |
| AHI (events/h) | 6.06 (4.14) | 22.13 (3.87) | 47.16 (13.68) | <0.001 * | 6.77 (4.27) | 20.73 (3.63) | 42.89 (7.89) | <0.001 * |
| Lowest O2 (%) | 88.26 (3.88) | 83.81 (4.89) | 78.44 (7.66) | <0.001 * | 86.94 (5.12) | 85.92 (4.09) | 78.00 (9.21) | <0.001 * |
| Desat.<90% (%) | 0.48 (2.17) | 1.56 (2.03) | 10.33 (14.66) | <0.001 * | 1.41 (7.41) | 2.53 (6.3) | 6.41 (8.0) | 0.013 * |
| ODI | 3.89 (3.39) | 15.54 (4.74) | 38.02 (16.21) | <0.001 * | 5.83 (13.41) | 13.2 (5.59) | 32.89 (11.88) | <0.001 * |
| cSBP (mmHg) | 114.99 (14.48) | 119.64 (17.13) | 119.24 (15.17) | 0.268 | 112.93 (12.32) | 116.38 (13.32) | 122.09 (10.92) | 0.014 * |
| cDBP (mmHg) | 73.02 (9.24) | 76.99 (10.16) | 78.43 (9.16) | 0.447 | 73.8 (8.97) | 75.25 (7.94) | 79.5 (8.53) | 0.037 * |
| baPWV (cm/s) | 1660.95 (305.45) | 1629.87 (259.07) | 1656.99 (288.97) | 0.711 | 1546.04 (189.67) | 1651.29 (197.18) | 1755.23 (243.78) | <0.001 * |
| CAVI | 5.89 (2.27) | 5.68 (1.75) | 5.96 (2.29) | 0.537 | 5.23 (1.26) | 6.05 (1.49) | 6.9 (2.15) | <0.001 * |
| hs-CRP (mg/dL) | 1.15 (1.3) | 1.34 (1.89) | 1.37 (1.82) | 0.642 | 0.69 (0.67) | 1.14 (1.9) | 1.62 (1.83) | 0.022 * |
Data are presented as means (s.d.).
$
Data are presented as number of subjects (% within each AHI group)
*
P<0.05, adjustment for gender and BMI for comorbid group
BMI, body mass index; PSQI, Pittsburgh sleep quality index; ESS, Epworth sleepiness scale; AHI, apnea-hypopnea index; Lowest O2, lowest O2 saturation during sleep study; Desat. < 90%, percentage of sleep with desaturation of oxygen below 90%; ODI, oxygen desaturation index; cSBP, central systolic blood pressure; cDBP, central diastolic blood pressure; baPWV, brachial-ankle pulse wave velocity; CAVI, cardio-ankle vascular index; hs-CRP, high-sensitivity C-reactive protein