Table 5.
Relationship between adiposity measures and blood TL among males and females a
Males (n=850) | Females (n=609) | |||
---|---|---|---|---|
|
||||
β (95% CI) | p b | β (95% CI) | p b | |
MODEL 1A | ||||
| ||||
Average BMI 1991–2005 | ||||
Linear term | 0.0015 (−0.013, 0.016) | 0.84 | 0.0022 (−0.019, 0.024) | 0.84 |
Quadratic term | −0.0013 (−0.0079, 0.0053) | 0.71 | 0.0078 (−0.0036, 0.019) | 0.18 |
Likelihood Ratio Test | 0.82 | 0.20 | ||
| ||||
MODEL 2A | ||||
| ||||
BMI z-score 1991 | −0.0011 (−0.017, 0.015) | 0.90 | −0.0025 (−0.024, 0.019) | 0.82 |
BMI z-score 1994 | −0.0076 (−0.023, 0.0079) | 0.34 | 0.019 (−0.0032, 0.042) | 0.09 |
BMI z-score 1998 | 0.00061 (−0.021, 0.019) | 0.95 | −0.014 (−0.04, 0.013) | 0.31 |
BMI z-score 2002 | 0.014 (−0.0055, 0.034) | 0.16 | −0.0078 (−0.036, 0.020) | 0.59 |
BMI z-score 2005 | −0.0012 (−0.017, 0.014) | 0.88 | −0.0055 (−0.029, 0.018) | 0.64 |
Likelihood Ratio Test | 0.63 | 0.35 | ||
| ||||
MODEL 1B | ||||
| ||||
Average waist circumference 1991–2005b | ||||
Linear term | 0.0029 (0.000088, 0.0056) | 0.04 | −0.0012 (−0.0037, 0.0013) | 0.34 |
Quadratic term | −0.00012 (−0.00022, – 0.000017) | 0.02 | 0.00013 (−0.000073, 0.00033) | 0.21 |
Likelihood Ratio Test | 0.10 | 0.37 | ||
| ||||
MODEL 2B | ||||
| ||||
Waist circumference 1998 c | 0.0012 (−0.00203, 0.0044) | 0.47 | −0.00048 (−0.0043, 0.0034) | 0.81 |
Waist circumference 2002 c | −0.00085 (−0.0045, 0.0028) | 0.64 | −0.00081 (−0.0046, 0.0030) | 0.68 |
Waist circumference 2005 c | 0.00056 (−0.0018, 0.0029) | 0.64 | 0.00038 (−0.0025, 0.0033) | 0.80 |
Likelihood Ratio Test | 0.74 | 0.90 |
All models control for mean-centered age in 2005 (in months), sex, the interaction between age and sex, log-transformed average inflation-adjusted income from 1983 to 2005, average urbanicity score from 1983 to 2005, smoking status (current, former, and never smoker), and ten principal component scores of genome-wide data.
All p-values are raw, unadjusted p-values. Significance levels in these models are set at an adjusted alpha value of 0.0125.
All models with waist circumference further controlled for mean-centered height and mean-centered age in each of the measurement periods.