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. 2016 Apr 27;6:100. doi: 10.3389/fonc.2016.00100

Figure 5.

Figure 5

Effect of EPTA-Gd and TPTA-Gd on the proliferation rates of human breast cancer cells. (A) Dose-dependent effect of EPTA-Gd on the proliferation rate of ER-positive T47D human breast cancer cells. (B) Dose-dependent effect of TPTA-Gd and of TPTA-Gd + E2 on the proliferation rate of ER-positive MCF7 human breast cancer cells. (C) Dose-dependent effect of EPTA-Gd on the proliferation rate of ER-negative WT MDA-MB-231 human breast cancer cells. Cell proliferation was measured by the cell viability MTT assay, and each data point represents mean ± SD of six-replicate wells. Control: cells cultivated in E2-free medium.