Table 1. Correlation between presence of DENV RNA in excreta and systemic viral dissemination.
Excreta | Head | Malpighiantubules | |
---|---|---|---|
Head | 0.90*** | ||
Malpighian tubules | 0.87** | 0.99*** | |
Midgut | 0.70 | 0.80* | 0.83** |
The table shows tetrachoric correlation coefficients for the pairwise presence or absence of DENV RNA in the excreta, head, midgut and Malpighian tubules of Ae. aegypti females previously exposed to DENV. Females were exposed to several virus doses (107 FFU/mL, 4 × 105 FFU/mL or 105 FFU/mL) and collected at different time points (days 5, 8 and 15 post exposure) to cover a range of vector competence phenotypes. Viral dissemination is inferred from detection of DENV RNA in head tissues and/or Malpighian tubules. P-values represent the statistical significance of the correlations based on Fisher exact test and adjusted for multiple testing (*p < 0.05, **p < 0.01, ***p < 0.001).