Table 4.

Susceptibilities of S. enterica serovar Typhimurium isolates to antibiotics after cpxR were deleted.

Strains	MICs (μg/mL)
	AMK	GEN	APR	NEO	CRO	CEF	CEQ
SH1	1.25	1	2	0.8	0.5	4	1
SH1ΔcpxR	0.625	0.125	0.5	12.8▴	0.5	2	1
SH2	5	32	4	0.4	0.5	4	0.5
SH2ΔcpxR	1.25	16	2	6.4▴	0.25	2	0.25
SH3	2	0.2	4	0.4	0.1	0.8	0.05
SH3ΔcpxR	0.5	0.1	1	6.4▴	0.05	0.4	0.05
SH4	1	0.4	2	0.4	0.05	0.8	0.1
SH4ΔcpxR	0.5	0.1	1	6.4▴	0.05	0.4	0.05
SH5	1	0.4	4	0.4	0.05	0.8	0.1
SH5ΔcpxR	0.5	0.2	2	3.2▴	0.05	0.4	0.05
SH6	0.4	0.2	8	0.8	0.1	0.2	0.1
SH6ΔcpxR	0.1	0.05	2	12.8▴	0.05	0.2	0.1
SH7	1.6	12.8	1024	1.6	0.1	1.6	0.2
SH7ΔcpxR	0.4	3.2	256	12.8▴	0.05	0.8	0.1
SH8	0.4	0.2	4	0.8	0.2	0.4	0.1
SH8ΔcpxR	0.2	0.1	2	12.8▴	0.05	0.1	0.05
SH9	0.8	0.4	4	0.8	0.1	0.8	0.05
SH9ΔcpxR	0.1	0.05	1	12.8▴	0.05	0.4	0.025

AMK, Amikacin; GEN, Gentamycin; APR, Apramycin; NEO, Neomycin; CRO, Ceftriaxone; CEF, Ceftiofur; CEQ, Cefquinome.

^▴High NEO resistance is present in strains because of the replacement of cpxR gene by the kanamycin-resistant gene (ΔcpxR::kan).