Table 2. Results for the 28 plasma levels of inflammatory factors and each of the three SEP factors.
| Father’s occupational position |
Participant’s education |
Household’s highest occupation |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| N | β (SE) | P-value | N | β (SE) | P-value | N | β (SE) | P-value | |
| (A) Inflammatory markers | |||||||||
| CCL11 | 234 | 0.18 (0.09) | 0.034 | 267 | −0.05 (0.08) | 0.546 | 237 | −0.02 (0.09) | 0.805 |
| CCL2 | 234 | 0.03 (0.05) | 0.518 | 267 | −0.05 (0.05) | 0.310 | 237 | −0.03 (0.05) | 0.544 |
| CCL7 | 234 | −0.05 (0.25) | 0.846 | 267 | −0.36 (0.23) | 0.117 | 237 | −0.47 (0.26) | 0.072 |
| CCL3 | 234 | −0.03 (0.18) | 0.868 | 267 | −0.27 (0.17) | 0.119 | 237 | −0.31 (0.19) | 0.103 |
| CCL4 | 234 | 0.23 (0.13) | 0.074 | 267 | −0.12 (0.12) | 0.292 | 237 | −0.14 (0.13) | 0.280 |
| CCL22 | 234 | 0.07 (0.11) | 0.497 | 267 | −0.1 (0.10) | 0.310 | 237 | −0.03 (0.11) | 0.799 |
| CX3CL1 | 234 | 0.13 (0.19) | 0.480 | 267 | −0.38 (0.17) | 0.026 | 237 | −0.2 (0.19) | 0.296 |
| CXCL1 | 234 | 0.20 (0.08) | 0.015 | 267 | −0.05 (0.08) | 0.506 | 237 | 0.02 (0.09) | 0.823 |
| CXCL10 | 234 | 0.10 (0.07) | 0.176 | 267 | −0.08 (0.07) | 0.244 | 237 | 0.00 (0.07) | 0.962 |
| CXCL8 | 234 | 0.07 (0.13) | 0.589 | 267 | −0.06 (0.13) | 0.613 | 237 | −0.09 (0.14) | 0.515 |
| IFNA2 | 234 | 0.51 (0.45) | 0.255 | 267 | −0.07 (0.42) | 0.876 | 237 | −0.27 (0.46) | 0.560 |
| IL1B | 234 | −0.04 (0.27) | 0.891 | 266 | −0.06 (0.25) | 0.799 | 237 | 0.08 (0.28) | 0.763 |
| IL2 | 234 | 0.31 (0.17) | 0.073 | 267 | −0.12 (0.17) | 0.481 | 237 | 0.32 (0.18) | 0.078 |
| IL4 | 234 | 0.40 (0.20) | 0.047 | 266 | 0.05 (0.18) | 0.793 | 237 | 0.12 (0.21) | 0.547 |
| IL5 | 234 | 0.17 (0.16) | 0.289 | 267 | 0.05 (0.15) | 0.755 | 237 | 0.21 (0.17) | 0.222 |
| IL6 | 234 | 0.13 (0.22) | 0.537 | 267 | 0.02 (0.21) | 0.934 | 237 | 0.24 (0.22) | 0.279 |
| IL7 | 234 | 0.19 (0.10) | 0.054 | 267 | −0.15 (0.09) | 0.113 | 237 | 0.03 (0.10) | 0.726 |
| IL10 | 234 | 0.10 (0.25) | 0.681 | 267 | −0.02 (0.24) | 0.929 | 237 | 0.05 (0.26) | 0.858 |
| IL13 | 234 | 0.05 (0.24) | 0.843 | 267 | −0.19 (0.23) | 0.413 | 237 | 0.15 (0.25) | 0.554 |
| IFNG | 234 | 0.18 (0.28) | 0.517 | 267 | −0.23 (0.28) | 0.403 | 237 | −0.13 (0.30) | 0.665 |
| CD40LG | 234 | 0.00 (0.09) | 0.993 | 267 | −0.04 (0.09) | 0.693 | 237 | 0.00 (0.09) | 0.970 |
| TNF | 234 | 0.13 (0.08) | 0.087 | 267 | 0.03 (0.08) | 0.686 | 237 | 0.08 (0.08) | 0.345 |
| EGF | 234 | −0.13 (0.27) | 0.625 | 267 | −0.58 (0.26) | 0.024 | 237 | −0.64 (0.28) | 0.024 |
| CSF3* | 234 | 0.29 (0.09) | 0.002 | 267 | 0.12 (0.09) | 0.154 | 237 | 0.15 (0.10) | 0.122 |
| CSF2 | 234 | 0.26 (0.14) | 0.062 | 267 | −0.16 (0.13) | 0.236 | 237 | 0.14 (0.15) | 0.338 |
| TGFA | 234 | 0.21 (0.29) | 0.476 | 267 | −0.19 (0.27) | 0.491 | 237 | −0.40 (0.30) | 0.184 |
| VEGFA | 234 | 0.06 (0.25) | 0.804 | 267 | −0.5 (0.23) | 0.031 | 237 | −0.48 (0.26) | 0.062 |
| FGF2 | 234 | −0.07 (0.24) | 0.755 | 267 | −0.34 (0.22) | 0.127 | 237 | −0.63 (0.24) | 0.010 |
| (B) Inflammatory scores | |||||||||
| Inflammatory score | 230 | 1.96 (0.89) | 0.029 | 230 | −1.02 (0.91) | 0.261 | 230 | −1.35 (0.93) | 0.151 |
| PC1 | 230 | −0.60 (0.45) | 0.182 | 230 | 0.66 (0.45) | 0.140 | 230 | 0.51 (0.46) | 0.268 |
Results are also presented for the inflammatory score and the first PC.
Model adjusted on age, gender, lymphoma case-control status, breast cancer case-control status, phase and center.
*Significant association with father’s occupational position after multiple testing correction (P < 0.0025).