Table 3. Life course multiple regression analyses for father’s occupational position and inflammatory status.
| Variables | Levels | Model A |
Model B-1 |
Model B-2 |
Model C |
Fully Adjusted Model |
|||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| β (SE) | P-value | β (SE) | P-value | β (SE) | P-value | β (SE) | P-value | β (SE) | P-value | ||
| (A) Plasma concentration of CSF3 | |||||||||||
| Father’s occupational position | Manual | 0.29 (0.09) | 0.002 | 0.27 (0.10) | 0.008 | 0.29 (0.10) | 0.004 | 0.28 (0.10) | 0.008 | 0.28 (0.10) | 0.007 |
| Participant’s education | Low | 0.03 (0.10) | 0.733 | – | – | 0.04 (0.11) | 0.742 | 0.02 (0.12) | 0.868 | ||
| Household’s highest occupation | Manual | 0.01 (0.10) | 0.916 | −0.01 (0.11) | 0.957 | −0.02 (0.11) | 0.862 | ||||
| BMI | 0.02 (0.01) | 0.230 | |||||||||
| Smoking status | Former | −0.01 (0.12) | 0.917 | ||||||||
| Current | −0.01 (0.12) | 0.608 | |||||||||
| Alcohol | 0.001 (0.003) | 0.644 | |||||||||
| (B) Inflammatory score | |||||||||||
| Father’s occupational position | Manual | 1.96 (0.89) | 0.029 | 2.88 (0.97) | 0.003 | 2.64 (0.93) | 0.005 | 3.08 (0.98) | 0.002 | 2.93 (1.00) | 0.004 |
| Participant’s education | Low | −2.22 (0.98) | 0.024 | – | – | −1.54 (1.08) | 0.156 | −1.5 (1.10) | 0.174 | ||
| Household’s highest occupation | Manual | −2.22 (0.97) | 0.023 | −1.56 (1.07) | 0.149 | −1.49 (1.09) | 0.174 | ||||
| BMI | −0.07 (0.13) | 0.617 | |||||||||
| Smoking status | Former | −0.62 (1.16) | 0.594 | ||||||||
| Current | −0.57 (1.16) | 0.621 | |||||||||
| Alcohol | −0.02 (0.03) | 0.433 | |||||||||
| (C) Principal component 1 | |||||||||||
| Father’s occupational position | Manual | −0.60 (0.45) | 0.182 | −1.05 (0.49) | 0.031 | −0.84 (0.47) | 0.074 | −1.10 (0.49) | 0.026 | −1.06 (0.50) | 0.034 |
| Participant’s education | Low | 1.10 (0.49) | 0.025 | – | – | 0.93 (0.54) | 0.088 | 0.95 (0.55) | 0.086 | ||
| Household’s highest occupation | Manual | 0.79 (0.49) | 0.104 | 0.39 (0.54) | 0.466 | 0.40 (0.55) | 0.462 | ||||
| BMI | −0.01 (0.07) | 0.856 | |||||||||
| Smoking status | Former | 0.27 (0.58) | 0.639 | ||||||||
| Current | 0.48 (0.58) | 0.411 | |||||||||
| Alcohol | 0.01 (0.01) | 0.637 | |||||||||
Results are presented for plasma concentration of CSF3 (A), and for the inflammatory score (B) and the first PC (C). Estimates are based on 230 participants with full SEP and lifestyle information.