Table 1. Impact of different genotypes on overall survival and progression free survival (in bold where statistically significant).
PFS | p | OS | p | |
---|---|---|---|---|
rs10434 | ||||
AA genotype (32, 23%) | 1.82 months | 6.51 months | ||
AG genotype (74, 54%) | 2.01 months | 7.89 months | ||
GG genotype (32, 23%) | 1.92 months | 0.14 | 4.67 months | 0.21 |
rs2010963 | ||||
GG genotype (62, 44%) | 1.84 months | 7.89 months | ||
CG genotype (56, 41%) | 1.94 months | 5.95 months | ||
CC genotype (20, 15%) | 4.28 months | 0.0098 | 9.08 months | 0.049 |
rs25648 | ||||
AA genotype (100, 72%) | 1.94 months | 6.51 months | ||
AT genotype (30, 22%) | 1.91 months | 7.99 months | ||
TT genotype (8, 6%) | 2.02 months | 0.96 | 9.38 months | 0.18 |
rs3025039 | ||||
AA genotype (120, 87%) | 1.91 months | 7.63 months | ||
AT genotype (16, 12%) | 3.12 months | 5.72 months | ||
TT genotype (2, 1%) | 1.84 months | 0.24 | 3.55 months | 0.06 |
rs699947 | ||||
CC genotype (44, 32%) | 2.07 months | 5.95 months | ||
AC genotype (56, 40%) | 2.01 months | 7.99 months | ||
AA genotype (38, 28%) | 1.84 months | 0.11 | 6.51 months | 0.46 |
rs833061 | ||||
TT genotype (44, 32%) | 2.07 months | 5.95 months | ||
TC genotype (56, 40%) | 2.01 months | 7.99 months | ||
CC genotype (38, 28%) | 1.84 months | 0.11 | 6.51 months | 0.46 |
rs4604006 | ||||
CC genotype (68, 49%) | 1.84 months | 7.8 months | ||
CT genotype (60, 43%) | 1.97 months | 5.95 months | ||
TT genotype (10, 8%) | 3.75 months | 0.50 | 13.16 months | 0.34 |
rs7664413 | ||||
CC genotype (80, 58%) | 1.84 months | 7.8 months | ||
CT genotype (52, 38%) | 1.97 months | 5.95 months | ||
TT genotype (6, 4%) | 3.75 months | 0.41 | NR | 0.07 |
rs664393 | ||||
CC genotype (106, 77%) | 2.01 months | 6.97 months | ||
CT genotype (30, 22%) | 1.84 months | 8.72 months | ||
TT genotype (2, 1%) | 1.48 months | <0.0001 | 5.95 months | 0.77 |
rs7993418 | ||||
genotype (68, 49%) | 1.84 months | 7.8 months | ||
AG genotype (64, 46%) | 1.97 months | 6.51 months | ||
GG genotype (6, 5%) | 5.3 months | 0.42 | 10.23 months | 0.32 |
rs1870377 | ||||
TT genotype (72, 52%) | 1.97 months | 7.63 months | ||
AT genotype (62, 45%) | 1.84 months | 7.8 months | ||
AA genotype (4, 3%) | 2.12 months | 0.98 | 3.54 months | 0.0061 |
rs2071559 | ||||
AA genotype (44, 32%) | 1.84 months | 6.51 months | ||
AG genotype (56, 40%) | 1.94 months | 7.8 months | ||
GG genotype (38, 28%) | 2.07 months | 0.86 | 5.92 months | 0.80 |
rs2305948 | ||||
CC genotype (114, 83%) | 1.94 months | 7.63 months | ||
CT genotype (24, 27%) | 1.84 months | 7.8 months | ||
TT genotype (0, 0%) | NA | 0.88 | NA | 0.81 |
rs7667298 | ||||
CC genotype (40, 29%) | 2.07 months | 5.92 months | ||
CT genotype (62, 45%) | 1.88 months | 7.8 months | ||
TT genotype (36, 26%) | 1.84 months | 0.46 | 7.99 months | 0.80 |
rs307805 | ||||
AA genotype (106, 77%) | 1.91 months | 7.63 months | ||
AG genotype (30, 22% | 2.07 months | 8.75 months | ||
GG genotype (2, 1%) | 2.3 months | 0.83 | 3.52 months | 0.0492 |
rs6877011 | ||||
CC genotype (110, 80%) | 1.97 months | 6.97 months | ||
CG genotype (28, 20%) | 1.86 months | 7.8 months | ||
GG genotype (0, 0%) | NA | 0.42 | NA | 0.48 |
rs307822 | ||||
CC genotype (104, 75%) | 1.97 months | 6.97 months | ||
CT genotype (34, 25%) | 1.84 months | 7.8 months | ||
TT genotype (0, 0%) | NA | 0.08 | NA | 0.67 |