Table 3.
Important publications on Antioxidants and Mitochondrial targets as AD therapeautics and preventive agents
| Anti-Oxidative stress agents | Therapeutics | References |
|---|---|---|
| Antioxidants | Vitamin C | Sano et al., 1997, Zandi et al., 2004 |
| Carotenoids | Javed et al., 2012; Vijayapadma et al., 2014 | |
| Resveratrol | Joseph et al., 2003; Ho et al., 2009 | |
| Curcumin | Yang et al., 2005, Ringman et al., 2012 | |
| Neu-P11 | He et al., 2013 | |
| Green tea and food additives | Kim et al., 2009; Zhao et al., 1989; Goodman et al., 1994; Iuvone et al., 2006 | |
| Mitochondrial targeting | Coenzyme Q10 (CoQ10) | Lee et al., 2009 |
| a-lipoic acid | Siedlak et al., 2009 | |
| MitoQ and plastoquinone | Kapay et al., 2011; McManus et al., 2011 | |
| SS31 | Calkins et al., 2011 | |
| Nrf2/ARE pathway targets | Tertbutylhydroquinone | Ramsey et al., 2007; Kanninen et al., 2008; Dumont et al., 2012 |
| Adenovirus-dependent gene delivery | Kanninen et al., 2008; Dumont et al., 2012 | |
| Metal Chelation | Desferrioxamine, EDTA and Clioquinol | Mandel et al., 2007; Amit et al., 2008; Hegde et al., 2009 |