Table 2.

Plasma lipid profiles (n=5) in experimental mice

		Wild C57BL/6 mouse					C57BL/6-Tlr4lps-del mouse
	wk
		Normal diet	HC diet				Normal diet	HC diet
		-	-	GroEL 200 μg/kg BW	GroEL 400 μg/kg BW	GST 400 μg/kg BW	-	-	GroEL 400 μg/kg BW
t-Cho (mg/dL)	0	105.4±.5.0	97.4±9.7	96.2±8.5	114.0±11.5	91.3±8.2	99.6±5.9	72.1±4.6	105.7±6.9
	2	103.5±4.6	369.6±28.2a	615.2±48.5a,c	595.8±33.5a,c	426.0±73.5a	108.9±9.7	343.2±56.9a	416.3±55.0a,d
	4	94.4±4.5	665.1±78.1a,b	761.9±85.1a,b	639.3±16.8a	660.4±55.2a,b	100.5±9.7	452.1±53.8a,b	645.3±77.0a,b
TG (mg/dL)	0	64.5±7.5	76.0±6.2	70.0±21.5	60.3±25.9	60.3±6.4	53.9±8.4	50.1±6.5	56.0±18.8
	2	66.9±6.4	107.3±9.8a	144.8±33.5a,c	162.5±35.1a,c	121.3±8.0a	45.3±16.5	145.2±30.9a	140.7±25.3a
	4	67.5±6.5	182.0±33.6a,b	267.3±22.8a,b,c	269.5±35.5a,b,c	186.0±32.8a,b	35.6±19.1	253.2±26.1a,b	236.0±34.9a,b
HDL (mg/dL)	0	42.4±14.2	59.8±5.4	56.6±9.2	53.5±14.2	53.6±14.2	40.2±13.8	52.1±13.6	42.7±18.7
	2	49.4±13.2	77.7±16.1	76.7±11.3	56.7±8.2	72.8±12.2	49.8±15.4	48.9±6.4	42.0±14.5
	4	41.8±14.2	79.6±7.2	69.7±10.2	62.6±7.4	63.6±16.2	44.6±9.1	44.2±16.1	45.3±15.3
LDL (mg/dL)	0	55.8±17.4	44.4±11.9	56.9±6.9	49.8±13.2	59.9±6.7	52.3±5.4	41.6±7.5	42.3±4.5
	2	41.1±11.2	271.9±27.9a	510.3±53.6a,c	507.7±35.6a,c	330.5±81.3a	31.2±6.8	242.8±89.1a	346.0±49.7a,d
	4	40.9±9.2	550.8±94.9a,b	639.5±94.6a,b	867.2±22.5a,b,c	512.3±51.2a,b	45.6±9.1	546.9±58.7a,b	637.7±79.8a,b,d

t-Cho, total-cholesterol; TG, triglyceride; HDL, high density lipoprotein; LDL, low density lipoprotein. Values are mean ± SD.

^a p<0.05 compared with 0 week at the same group;

^b p<0.05 compared with 2 week at the same group;

^c p<0.05 compared with group 2 (wild type C57BL/6 mice fed with HC diet) at the same time point;

^d p<0.05 compared with group 4 (wild type C57BL/6 mice fed with HC diet and received 400 μg/kg BW of GroEL) at the same time point.