Table 3.

Associations between single-nucleotide polymorphisms and keloid susceptibility in the Chinese population relative to the controls

SNP	Allele (risk)	Mode	Odds ratio (95% CI)	P-value	Power
1) Mild-moderate keloid vs control
rs873549	A/G (G)	Dominant	3.415 (1.826-6.385)	4.40E-05	100
		Recessive	3.159 (1.887-5.287)	4.03E-06	100
		Allele	2.428 (1.728-3.414)	1.38E-07	100
rs1511412	G/A (A)	Dominant	1.108 (1.151-8.134)	0.92	5
		Recessive	NaN	NaN	NaN
		Allele	1.107 (0.1519-8.068)	0.9201	5
rs2118610	A/G (G)	Dominant	Inf	1	NaN
		Recessive	1.04 (0.565-1.913)	0.9	7
		Allele	1.111 (0.624-1.976)	0.7211	12
rs2271289	T/C (C)	Dominant	1.713 (0.596-4.927)	0.312	100
		Recessive	1.088 (0.507-02.333)	0.829	16
		Allele	1.212 (0.721-2.036)	0.4679	45
2) Severe keloids vs control
rs873549	A/G (G)	Dominant	1.447 (1.096-1.909)	9.00E-03	99
		Recessive	2.482 (1.836-3.357)	1.17E-09	100
		Allele	1.599 (1.327-1.925)	6.33E-07	100
rs1511412	G/A (A)	Dominant	2.581 (1.211-5.504)	0.011	91
		Recessive	NaN	NaN	NaN
		Allele	2.554 (1.205-5.414)	0.01119	29
rs2118610	A/G (G)	Dominant	1.532 (0.37-6.34)	0.553	18
		Recessive	1.084 (0.774-1.518)	0.64	12
		Allele	1.097 (0.803-1.5)	0.5606	11
rs2271289	T/C (C)	Dominant	4.085 (1.781-9.372)	3.25E-04	100
		Recessive	1.67 (1.114-2.504)	1.20E-02	100
		Allele	1.7718 (1.3063-2.4033)	0.0001953	100

Abbreviations: CI, confidence interval; SNP, single-nucleotide polymorphism.