Table 4.

Associations between single-nucleotide polymorphisms and keloid susceptibility in the Chinese population relative to the controls

SNP	Allele (risk)	Mode	Odds ratio (95% CI)	P-value	Power
1) Family-history keloid vs control
rs873549	A/G (G)	Dominant	1.536 (0.922-2.559)	0.097	100
		Recessive	1.875 (1.05-3.348)	0.031	100
		Allele	1.48 (1.055-2.079)	0.02255	100
rs1511412	G/A (A)	Dominant	2.215 (0.528-9.288)	0.24	73
		Recessive	NA	NA	NA
		Allele	2.198 (0.5296-9.118)	0.2659	37
rs2118610	A/G (G)	Dominant	0.883 (0.12-6.489)	0.594	6
		Recessive	1.296 (0.677-2.481)	0.433	68
		Allele	1.2324 (0.6789-2.238)	0.4915	34
rs2271289	T/C (C)	Dominant	2.548 (0.773-8.391)	0.111	100
		Recessive	1.919 (0.954-3.86)	0.063	100
		Allele	1.777 (1.045-3.022)	0.03152	100
2) No-family-history keloid vs control
rs873549	A/G (G)	Dominant	1.761 (1.321-2.347)	9.45E-05	100
		Recessive	2.869 (2.14-3.847)	2.39E-13	100
		Allele	1.844 (1.532-2.221)	5.91E-11	100
rs1511412	G/A (A)	Dominant	2.259 (1.014-5.033)	0.041	76
		Recessive	NA	NA	NA
		Allele	2.24 (1.001-4.963)	0.04129	40
rs2118610	A/G (G)	Dominant	3.065 (0.421-22.293)	0.365	71
		Recessive	1.02 (0.732-1.422)	0.905	6
		Allele	1.0664 (0.7825-1.4539)	0.6843	8
rs2271289	T/C (C)	Dominant	3.388 (1.562-7.349)	0.001	100
		Recessive	1.401 (0.925-2.122)	0.11	98
		Allele	1.5667 (1.1589-2.1178)	0.003274	100

Abbreviations: CI, confidence interval; SNP, single-nucleotide polymorphism.