Table 5.

Associations between single-nucleotide polymorphisms and keloid susceptibility in the Chinese population relative to the controls

SNP	Allele (risk)	Mode	Odds ratio (95% CI)	P-value	Power
1) Multiple keloids vs controls
rs873549	A/G (G)	Dominant	2.033 (1.376-3.006)	2.84E-04	100
		Recessive	2.479 (1.673-3.675)	3.06E-06	100
		Allele	1.841 (1.442-2.35)	6.66E-07	100
rs1511412	G/A (A)	Dominant	2.854 (1.121-7.271)	0.021	97
		Recessive	NA	NA	NA
		Allele	2.819 (1.116-7.122)	0.02195	70
rs2118610	A/G (G)	Dominant	1.74 (0.239-12.697)	1	32
		Recessive	1.137 (0.726-1.78)	0.575	24
		Allele	1.1504 (0.7576-1.747)	0.511	19
rs2271289	T/C (C)	Dominant	3.795 (1.526-9.436)	0.002	100
		Recessive	1.632 (1.032-2.579)	0.035	100
		Allele	1.731 (1.2284-2.439)	0.001515	100
2) Single keloids vs controls
rs873549	A/G (G)	Dominant	1.463 (1.056-2.028)	0.021	99
		Recessive	2.655 (1.877-3.757)	1.11E-08	100
		Allele	1.651 (1.327-2.053)	5.39E-06	100
rs1511412	G/A (A)	Dominant	1.349 (0.417-4.369)	0.494	12
		Recessive	NA	NA	NA
		Allele	1.346 (0.418-4.336)	0.617	7
rs2118610	A/G (G)	Dominant	2.169 (0.298-15.802)	0.723	49
		Recessive	1.044 (0.705-1.548)	0.828	7
		Allele	1.0778185 (0.7468-1.555)	0.6888	9
rs2271289	T/C (C)	Dominant	2.477 (0.981-6.256)	0.047	100
		Recessive	1.36 (0.773-2.39)	0.284	95
		Allele	1.4626 (0.9756-2.1925)	0.06402	99

Abbreviations: CI, confidence interval; SNP, single-nucleotide polymorphism.