Table 6.
Pathway identification result annotation by KOBAS
| Term | Database | ID | P-Value |
|---|---|---|---|
| Downregulation of ErbB4 signaling | Reactome | REACT_115828 | 0.00107219 |
| Antiviral mechanism by IFN-stimulated genes | Reactome | REACT_115676 | 0.009080363 |
| ISG15 antiviral mechanism | Reactome | REACT_115831 | 0.009080363 |
| ErbB4 signaling events | PID | erbb4_pathway | 0.0123517 |
| Ubiquitin mediated proteolysis | KEGG PATHWAY | hsa04120 | 0.016877622 |
| Presenilin action in Notch and Wnt signaling | PID | ps1pathway | 0.017560936 |
| Signaling by ERBB4 | Reactome | REACT_115596 | 0.018349439 |
| Epstein-Barr virus infection | KEGG PATHWAY | hsa05169 | 0.024760998 |
| Interferon Signaling | Reactome | REACT_25229 | 0.025314945 |
| Signaling events mediated by VEGFR1 and VEGFR2 | PID | vegfr1_2_pathway | 0.025709817 |
| Endocytosis | KEGG PATHWAY | hsa04144 | 0.026090925 |
| Antigen processing: Ubiquitination & Proteasome degradation | Reactome | REACT_75842 | 0.028323707 |
| Class I MHC mediated antigen processing & presentation | Reactome | REACT_75820 | 0.034186008 |
| Cytokine Signaling in Immune system | Reactome | REACT_75790 | 0.03962846 |
| Adaptive Immune System | Reactome | REACT_75774 | 0.078446738 |
| Immune System | Reactome | REACT_6900 | 0.144650849 |
| Signal Transduction | Reactome | REACT_111102 | 0.24090275 |
Databases: BioCarta, Gene Ontology, GAD, FunDO, KEGG PATHWAY, OMIM, PID, PANTHER, Reactome, BioCyc, NHGRI GWAS Catalog, KEGG DISEASE. Statistical test method: hypergeometric test/Fisher’s exact test.