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. 2016 Feb 15;8(2):719–731.

Figure 6.

Figure 6

MiR-99a inhibits EC growth in vivo. A. Graphic representing tumor volumes at the end of the experiment for mice treated with miR-99a mimic or scramble mimic. Four mice per group; B. Tumor volume averages between scramble and miR-99a mimic treated mice groups at the indicated days during the experiment; C. Tumor weight averages between scramble and miR-99a mimic treated mice groups at the end of the experiment (28 days); D. Quantitative RT-PCR analysis showed the relative expression of miR-99a in injected tumor tissues (normalized to U6); E. Representative images of the immunohistochemistry analysis of AKT1, mTOR and caspase-3 in tumors from xenograft mice. Data are presented as means ± SD. Statistical analysis was carried out using ANOVA. **P<0.01.